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Conformational Preferences of α-Substituted Proline Analogues
DFT calculations at the B3LYP/6-31+G(d,p) level have been used to investigate how the replacement of the α hydrogen by a more sterically demanding group affects the conformational preferences of proline. Specifically, the N-acetyl-N’-methylamide derivatives of L-proline, L-α-methylproline and L-α-ph...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2679371/ https://ncbi.nlm.nih.gov/pubmed/18351745 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo702710x |
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