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Preparation of a Library of Unsymmetrical Ureas Based on 8-Azabicyclo [3.2.1]Octane Scaffold

This paper reports the preparation of a library of unsymmetrical ureas based on 8-azabicyclo [3.2.1]octane scaffold. The reported synthetic route uses nortropane-8-carbonyl chlorides as key intermediates that, when treated with a slight excess of amine, give the corresponding ureas in high yield (12...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Agarkov, Anton, Gilbertson, Scott R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3086471/
https://ncbi.nlm.nih.gov/pubmed/18611055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cc800068k
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