Determination of Salirasib (S-trans, trans-farnesylthiosalicylic acid) in human plasma using liquid chromatography-tandem mass spectrometry

A liquid chromatography/tandem mass spectrometric (LC/MS/MS) assay was developed for the quantitative determination of salirasib (S-trans, trans-farnesylthiosalicylic acid, FTS) in human plasma. Sample pretreatment involved liquid-liquid extraction with methyl t-butyl ether of 0.5-mL aliquots of lit...

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Bibliografiske detaljer
Main Authors: Zhao, Ming, He, Ping, Xu, Linping, Hidalgo, Manuel, Laheru, Dan, Rudek, Michelle A.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3086377/
https://ncbi.nlm.nih.gov/pubmed/18534927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2008.05.028
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