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Chronic Exposure to a TLR Ligand Injures Hematopoietic Stem Cells
Hematopoietic stem cells (HSC) can be harmed by disease, chemotherapy, radiation and normal aging. We now show that damage also occurs in mice repeatedly treated with very low doses of lipopolysaccharide (LPS). Overall health of the animals was good, and there were relatively minor changes in marrow...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3086167/ https://ncbi.nlm.nih.gov/pubmed/21441445 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003438 |
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