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Label-free quantitative proteomics and SAINT analysis enable interactome mapping for the human Ser/Thr protein phosphatase 5

Affinity-purification coupled to mass spectrometry (AP-MS) represents a powerful and proven approach for the analysis of protein-protein interactions. However, the detection of true interactions for proteins that are commonly considered background contaminants is currently a limitation of AP-MS. Her...

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Bibliografiska uppgifter
Huvudupphovsmän: Skarra, Dana V., Goudreault, Marilyn, Choi, Hyungwon, Mullin, Michael, Nesvizhskii, Alexey I., Gingras, Anne-Claude, Honkanen, Richard E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3086140/
https://ncbi.nlm.nih.gov/pubmed/21360678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.201000770
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