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Small Molecule Inhibitors of Ser/thr Protein Phosphatases: Specificity, Use and Common Forms of Abuse

Natural product extracts have proven to be a rich source of small molecules that potently inhibit the catalytic activity of certain PPP-family ser/thr protein phosphatases. To date, the list of inhibitors includes, okadaic acid (produced by marine dionoflagelates, Prorocentrum sp. and Dinophysis sp....

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Main Authors: Swingle, Mark, Ni, Li, Honkanen, Richard E.
Format: Artigo
Jezik:Inglês
Izdano: 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709456/
https://ncbi.nlm.nih.gov/pubmed/17200551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1385/1-59745-267-X:23
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