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Differential roles of nitric oxide synthase isozymes in cardiotoxicity and mortality following chronic doxorubicin treatment in mice

The roles of individual nitric oxide synthases (NOS) in anthracycline-related cardiotoxicity are not completely understood. We investigated the effects of a chronic treatment with doxorubicin (DOX) on knockouts of the individual NOS isozymes and on transgenic mice with myocardial overexpression of e...

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Bibliografiske detaljer
Main Authors: Deng, Shiwei, Kruger, Anke, Schmidt, Albrecht, Metzger, Annegret, Yan, Tiandong, Gödtel-Armbrust, Ute, Hasenfuss, Gerd, Brunner, Friedrich, Wojnowski, Leszek
Format: Artigo
Sprog:Inglês
Udgivet: Springer-Verlag 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3085792/
https://ncbi.nlm.nih.gov/pubmed/19308358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00210-009-0407-y
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