A Phase II Trial of 17-Allylamino-17-Demethoxygeldanamycin (17-AAG) in Patients with Hormone-Refractory Metastatic Prostate Cancer

PURPOSE: 17-Allylamino-17-Demethoxygeldanamycin (17-AAG) is a benzoquinone ansamycin antibiotic with anti-proliferative activity in several mouse xenograft models including prostate cancer models. A two-stage phase II study was conducted to assess the activity and toxicity profile of 17-AAG administ...

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Detalhes bibliográficos
Main Authors: Heath, Elisabeth I., Hillman, David W., Vaishampayan, Ulka, Sheng, Shijie, Sarkar, Fazlul, Harper, Felicity, Gaskins, Melvin, Pitot, Henry C., Tan, Winston, Ivy, S. Percy, Pili, Roberto, Carducci, Michael A., Liu, Glenn
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3085545/
https://ncbi.nlm.nih.gov/pubmed/19047126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-0221
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