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Insights into the Mechanical Properties of the Kinesin Neck Linker Domain from Sequence Analysis and Molecular Dynamics Simulations
The 14–18 amino acid kinesin neck linker domain links the core motor to the coiled-coil dimerization domain. One puzzle is that the neck linker appears too short for the 4 nm distance each linker must stretch to enable an 8 nm step – when modeled as an entropic spring, high inter-head forces are pre...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3085455/ https://ncbi.nlm.nih.gov/pubmed/21544223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12195-009-0059-5 |
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