Cellulase Linkers Are Optimized Based on Domain Type and Function: Insights from Sequence Analysis, Biophysical Measurements, and Molecular Simulation

Cellulase enzymes deconstruct cellulose to glucose, and are often comprised of glycosylated linkers connecting glycoside hydrolases (GHs) to carbohydrate-binding modules (CBMs). Although linker modifications can alter cellulase activity, the functional role of linkers beyond domain connectivity rema...

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Detaylı Bibliyografya
Asıl Yazarlar: Sammond, Deanne W., Payne, Christina M., Brunecky, Roman, Himmel, Michael E., Crowley, Michael F., Beckham, Gregg T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2012
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3490864/
https://ncbi.nlm.nih.gov/pubmed/23139804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048615
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