Incorporating age at onset of smoking into genetic models for nicotine dependence: Evidence for interaction with multiple genes

Nicotine dependence is moderately heritable, but identified genetic associations explain only modest portions of this heritability. We analyzed 3,369 SNPs from 349 candidate genes, and investigated whether incorporation of SNP-by-environment interaction into association analyses might bolster gene d...

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Detalhes bibliográficos
Main Authors: Grucza, Richard A., Johnson, Eric O., Krueger, Robert F., Breslau, Naomi, Saccone, Nancy L., Chen, Li-Shiun, Derringer, Jaime, Agrawal, Arpana, Lynskey, Micheal, Bierut, Laura J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3085318/
https://ncbi.nlm.nih.gov/pubmed/20624154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1369-1600.2010.00220.x
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