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Multiple cholinergic nicotinic receptor genes affect nicotine dependence risk in African and European Americans

Several independent studies show that the chromosome 15q25.1 region, which contains the CHRNA5-CHRNA3-CHRNB4 gene cluster, harbors variants strongly associated with nicotine dependence, other smoking behaviors, lung cancer, and chronic obstructive pulmonary disease. We investigated whether variants...

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Autori principali: Saccone, Nancy L., Schwantes-An, Tae-Hwi, Wang, Jen C., Grucza, Richard A., Breslau, Naomi, Hatsukami, Dorothy, Johnson, Eric O., Rice, John P., Goate, Alison M., Bierut, Laura J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2970751/
https://ncbi.nlm.nih.gov/pubmed/20584212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1601-183X.2010.00608.x
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