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Quantifying protein–protein interactions in high throughput using protein domain microarrays

Protein microarrays provide an efficient way to identify and quantify protein–protein interactions in high throughput. One drawback of this technique is that proteins show a broad range of physicochemical properties and are often difficult to produce recombinantly. To circumvent these problems, we h...

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Bibliographic Details
Main Authors: Kaushansky, Alexis, Allen, John E, Gordus, Andrew, Stiffler, Michael A, Karp, Ethan S, Chang, Bryan H, MacBeath, Gavin
Format: Artigo
Language:Inglês
Published: 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3085283/
https://ncbi.nlm.nih.gov/pubmed/20360771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2010.36
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