PET imaging of CXCR4 using copper-64 labeled peptide antagonist

Expression of CXCR4 in cancer has been found to correlate with poor prognosis and resistance to chemotherapy. In this study we developed a derivative of the CXCR4 peptide antagonist, T140-2D, that can be labeled easily with the PET isotope copper-64, and thereby enable in vivo visualization of CXCR4...

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Bibliographische Detailangaben
Hauptverfasser: Jacobson, Orit, Weiss, Ido D., Szajek, Lawrence P., Niu, Gang, Ma, Ying, Kiesewetter, Dale O., Farber, Joshua M., Chen, Xiaoyuan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2011
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3085282/
https://ncbi.nlm.nih.gov/pubmed/21544263
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