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(64)Cu-AMD3100 - A novel imaging agent for targeting chemokine receptor CXCR4

CXCR4 is a chemokine receptor which has been shown to be exploited by various tumors for increased survival, invasion, and homing to target organs. We developed a one step radiosynthesis for labeling the CXCR4-specific antagonist AMD3100 with Cu-64 to produce (64)Cu-AMD3100 with a specific activity...

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Detalhes bibliográficos
Main Authors: Jacobson, Orit, Weiss, Ido D., Szajek, Lawrence, Farber, Joshua, Kiesewetter, Dale O.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2723765/
https://ncbi.nlm.nih.gov/pubmed/19188071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2009.01.014
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