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Positron Emission Tomography Imaging of Tumors Expressing the Human Chemokine Receptor CXCR4 in Mice with the Use of (64)Cu-AMD3100

PURPOSE: Expression of CXCR4 in cancers has been correlated with poor prognosis and increased metastasis. Quantifying CXCR4 expression non-invasively might aid in prognostication and monitoring therapy. We evaluated a radiolabeled antagonist of CXCR4, (64)Cu-AMD3100, as a positron-emitting imaging a...

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Detalhes bibliográficos
Publicado no:Mol Imaging Biol
Main Authors: Weiss, Ido D., Jacobson, Orit, Kiesewetter, Dale O., Jacobus, John P., Szajek, Lawrence P., Chen, Xiaoyuan, Farber, Joshua M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5264522/
https://ncbi.nlm.nih.gov/pubmed/21347799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-010-0466-y
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