Iron: A Pathological Mediator of Alzheimer Disease?

Metal-catalyzed oxidation and free radical formation are potent mediators of cellular injury to every category of macromolecule found in vulnerable neuronal populations and are thought to play an early and central role in Alzheimer disease (AD) pathogenesis. While metal-binding sites are present in...

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Autori principali: Rolston, Raj K., Perry, George, Zhu, Xiongwei, Castellani, Rudy J., Dwyer, Barney E., Lee, Hyoung-gon, Petersen, Robert B., Smith, Mark A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3085186/
https://ncbi.nlm.nih.gov/pubmed/21544251
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