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Hypocretin 1/orexin A in the ventral tegmental area enhances dopamine responses to cocaine and promotes cocaine self-administration

RATIONALE: Recent evidence indicates that the hypocretin/orexin system participates in the regulation of reinforcement and addiction processes. For example, manipulations that decrease hypocretin neurotransmission result in disruptions of neurochemical and behavioral responses to cocaine. OBJECTIVES...

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Main Authors: España, Rodrigo A., Melchior, James R., Roberts, David C. S., Jones, Sara R.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3085140/
https://ncbi.nlm.nih.gov/pubmed/20959967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-010-2048-8
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