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Identification of a 59 bp enhancer located at the first exon/intron boundary of the human O6-methylguanine DNA methyltransferase gene.

The DNA repair enzyme, O6-methylguanine DNA methyltransferase (MGMT) is responsible for repair of damage induced by alkylating agents that produce adducts at O6-guanine in DNA. Although the MGMT gene promoter has housekeeping gene promoter characteristics, unlike these genes which are expressed at a...

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Publicat a:Nucleic Acids Res
Autors principals: Harris, L C, Remack, J S, Brent, T P
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 1994
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC308508/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7984409/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/22.22.4614
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