An ENU-Mutagenesis Screen in the Mouse: Identification of Novel Developmental Gene Functions

BACKGROUND: Mutagenesis screens in the mouse have been proven useful for the identification of novel gene functions and generation of interesting mutant alleles. Here we describe a phenotype-based screen for recessive mutations affecting embryonic development. METHODOLOGY/PRINCIPAL FINDINGS: Mice we...

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Autors principals: Wansleeben, Carolien, van Gurp, Léon, Feitsma, Harma, Kroon, Carla, Rieter, Ester, Verberne, Marlies, Guryev, Victor, Cuppen, Edwin, Meijlink, Frits
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084836/
https://ncbi.nlm.nih.gov/pubmed/21559415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019357
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