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Interaction of Bestrophin-1 and Ca(2+) Channel β-Subunits: Identification of New Binding Domains on the Bestrophin-1 C-Terminus

Bestrophin-1 modulates currents through voltage-dependent L-type Ca(2+) channels by physically interacting with the β-subunits of Ca(2+) channels. The main function of β-subunits is to regulate the number of pore-forming Ca(V)-subunits in the cell membrane and modulate Ca(2+) channel currents. To un...

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Autors principals: Milenkovic, Vladimir M., Krejcova, Sarka, Reichhart, Nadine, Wagner, Andrea, Strauß, Olaf
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084833/
https://ncbi.nlm.nih.gov/pubmed/21559412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019364
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