Retroviral vector sequences inhibit human beta-globin gene expression in transgenic mice.
The DNase I hypersensitive site 5' HS2 of the human beta-globin locus control region confers position-independent, high-level expression on the human beta-globin gene in transgenic mice. When a 5' HS2 beta-globin construct is flanked by retroviral vector sequences derived from Moloney Murine Leukemi...
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| Veröffentlicht in: | Nucleic Acids Res |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
1994
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| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC308482/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7971278/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/22.21.4477 |
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