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Retroviral vector sequences inhibit human beta-globin gene expression in transgenic mice.

The DNase I hypersensitive site 5' HS2 of the human beta-globin locus control region confers position-independent, high-level expression on the human beta-globin gene in transgenic mice. When a 5' HS2 beta-globin construct is flanked by retroviral vector sequences derived from Moloney Muri...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: McCune, S L, Townes, T M
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 1994
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC308482/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7971278/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/22.21.4477
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