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Mamld1 Knockdown Reduces Testosterone Production and Cyp17a1 Expression in Mouse Leydig Tumor Cells

BACKGROUND: MAMLD1 is known to be a causative gene for hypospadias. Although previous studies have indicated that MAMLD1 mutations result in hypospadias primarily because of compromised testosterone production around the critical period for fetal sex development, the underlying mechanism(s) remains...

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Detalhes bibliográficos
Main Authors: Nakamura, Michiko, Fukami, Maki, Sugawa, Fumihiro, Miyado, Mami, Nonomura, Katsuya, Ogata, Tsutomu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084764/
https://ncbi.nlm.nih.gov/pubmed/21559465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019123
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