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Mamld1 Deficiency Significantly Reduces mRNA Expression Levels of Multiple Genes Expressed in Mouse Fetal Leydig Cells but Permits Normal Genital and Reproductive Development

Although mastermind-like domain containing 1 (MAMLD1) (CXORF6) on human chromosome Xq28 has been shown to be a causative gene for 46,XY disorders of sex development with hypospadias, the biological function of MAMLD1/Mamld1 remains to be elucidated. In this study, we first showed gradual and steady...

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Detalhes bibliográficos
Main Authors: Miyado, Mami, Nakamura, Michiko, Miyado, Kenji, Morohashi, Ken-ichirou, Sano, Shinichiro, Nagata, Eiko, Fukami, Maki, Ogata, Tsutomu
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3512063/
https://ncbi.nlm.nih.gov/pubmed/23087174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-1324
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