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Expression of Xenobiotic Biomarkers CYP1 Family in Preputial Tissue of Patients with Hypospadias and Phimosis and Its Association with DNA Methylation Level of SRD5A2 Minimal Promoter

Several epidemiological studies have suggested that the incidence of male reproductive organ malformations, including hypospadias or cryptorchidism, has increased due to fetal-stage exposure to environmental pollutants. However, the association of chemical exposure with the expression of target regu...

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Detalhes bibliográficos
Publicado no:Arch Environ Contam Toxicol
Main Authors: Ohsako, Seiichiroh, Aiba, Toshiki, Miyado, Mami, Fukami, Maki, Ogata, Tsutomu, Hayashi, Yutaro, Mizuno, Kentaro, Kojima, Yoshiyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5807475/
https://ncbi.nlm.nih.gov/pubmed/29080015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00244-017-0466-x
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