Organometallic Iron(III)-Salophene Exerts Cytotoxic Properties in Neuroblastoma Cells via MAPK Activation and ROS Generation

The objective of the present study was to investigate the specific effects of Iron(III)-salophene (Fe-SP) on viability, morphology, proliferation, cell cycle progression, ROS generation and pro-apoptotic MAPK activation in neuroblastoma (NB) cells. A NCI-DTP cancer screen revealed that Fe-SP display...

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Bibliografiska uppgifter
Huvudupphovsmän: Kim, Kyu Kwang, Singh, Rakesh K., Strongin, Robert M., Moore, Richard G., Brard, Laurent, Lange, Thilo S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2011
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084742/
https://ncbi.nlm.nih.gov/pubmed/21559503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019049
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