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Effect of Indole Ethyl Isothiocyanates on Proliferation, Apoptosis and MAPK Signaling in Neuroblastoma Cell Lines

Several indole ethyl isothiocyanate (IEITC) analogs were designed, synthesized and screened to evaluate their cytotoxicity against neuroblastoma (NB) cells in-vitro. In NB, predominantly a tumor of early childhood, survival remains low despite aggressive treatments. Therefore, novel treatment strate...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Singh, Rakesh K., Lange, Thilo S., Kim, Kyu Kwang, Zou, Yongping, Lieb, Casey, Sholler, Giselle L., Brard, Laurent
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2093989/
https://ncbi.nlm.nih.gov/pubmed/17855093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2007.08.032
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