Induction of cytotoxicity, apoptosis and cell cycle arrest by 1-t-butyl carbamoyl, 7-methyl-indole-3-ethyl isothiocyanate (NB7M) in nervous system cancer cells

Our group has recently developed 1-(t)butyl carbamoyl, 7-methyl-indole-3-ethyl isothiocyanate (NB7M), a novel indole ethyl isothiocyanate analog. We now describe its selective cytotoxicity in both central nervous system (CNS) and neuroblastoma (NB) cancer cells. In an effort to understand its mechan...

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Bibliographic Details
Main Authors: Brard, Laurent, Singh, Rakesh K, Kim, Kyu Kwang, Lange, Thilo S, Sholler, Giselle L Saulier
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2009
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761180/
https://ncbi.nlm.nih.gov/pubmed/19920894
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