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Induction of cytotoxicity, apoptosis and cell cycle arrest by 1-t-butyl carbamoyl, 7-methyl-indole-3-ethyl isothiocyanate (NB7M) in nervous system cancer cells

Our group has recently developed 1-(t)butyl carbamoyl, 7-methyl-indole-3-ethyl isothiocyanate (NB7M), a novel indole ethyl isothiocyanate analog. We now describe its selective cytotoxicity in both central nervous system (CNS) and neuroblastoma (NB) cancer cells. In an effort to understand its mechan...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Brard, Laurent, Singh, Rakesh K, Kim, Kyu Kwang, Lange, Thilo S, Sholler, Giselle L Saulier
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Dove Medical Press 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761180/
https://ncbi.nlm.nih.gov/pubmed/19920894
Tagiau: Ychwanegu Tag
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