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Identification of Broad-Based HIV-1 Protease Inhibitors From Combinatorial Libraries

Clinically approved inhibitors of HIV-1 protease function via a competitive mechanism. A particular vulnerability of competitive inhibitors is their sensitivity to increases in substrate concentration, as may occur during virion assembly, budding and processing into a mature, infectious viral partic...

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Bibliografische gegevens
Hoofdauteurs: Chang, Max W., Giffin, Michael J., Muller, Rolf, Savage, Jeremiah, Lin, Ying C., Hong, Sukwon, Jin, Wei, Whitby, Landon R., Elder, John H., Boger, Dale L., Torbett, Bruce E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084599/
https://ncbi.nlm.nih.gov/pubmed/20507280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20091645
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