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Identification of Broad-Based HIV-1 Protease Inhibitors From Combinatorial Libraries
Clinically approved inhibitors of HIV-1 protease function via a competitive mechanism. A particular vulnerability of competitive inhibitors is their sensitivity to increases in substrate concentration, as may occur during virion assembly, budding and processing into a mature, infectious viral partic...
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| Autori principali: | , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3084599/ https://ncbi.nlm.nih.gov/pubmed/20507280 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20091645 |
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