Identification of Broad-Based HIV-1 Protease Inhibitors From Combinatorial Libraries

Clinically approved inhibitors of HIV-1 protease function via a competitive mechanism. A particular vulnerability of competitive inhibitors is their sensitivity to increases in substrate concentration, as may occur during virion assembly, budding and processing into a mature, infectious viral partic...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Chang, Max W., Giffin, Michael J., Muller, Rolf, Savage, Jeremiah, Lin, Ying C., Hong, Sukwon, Jin, Wei, Whitby, Landon R., Elder, John H., Boger, Dale L., Torbett, Bruce E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084599/
https://ncbi.nlm.nih.gov/pubmed/20507280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20091645
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge