Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

Genome-wide association studies (GWAS) and candidate gene studies in ulcerative colitis (UC) have identified 18 susceptibility loci. We conducted a meta-analysis of 6 UC GWAS, comprising 6,687 cases and 19,718 controls, and followed-up the top association signals in 9,628 cases and 12,917 controls....

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Prif Awduron: Anderson, Carl A., Boucher, Gabrielle, Lees, Charlie W., Franke, Andre, D’Amato, Mauro, Taylor, Kent D., Lee, James C., Goyette, Philippe, Imielinski, Marcin, Latiano, Anna, Lagacé, Caroline, Scott, Regan, Amininejad, Leila, Bumpstead, Suzannah, Baidoo, Leonard, Baldassano, Robert N., Barclay, Murray, Bayless, Theodore M., Brand, Stephan, Büning, Carsten, Colombel, Jean-Frédéric, Denson, Lee A., De Vos, Martine, Dubinsky, Marla, Edwards, Cathryn, Ellinghaus, David, Fehrmann, Rudolf S.N., Floyd, James A.B., Florin, Tim, Franchimont, Denis, Franke, Lude, Georges, Michel, Glas, Jürgen, Glazer, Nicole L., Guthery, Stephen L., Haritunians, Talin, Hayward, Nicholas K., Hugot, Jean-Pierre, Jobin, Gilles, Laukens, Debby, Lawrance, Ian, Lémann, Marc, Levine, Arie, Libioulle, Cecile, Louis, Edouard, McGovern, Dermot P., Milla, Monica, Montgomery, Grant W., Morley, Katherine I., Mowat, Craig, Ng, Aylwin, Newman, William, Ophoff, Roel A, Papi, Laura, Palmieri, Orazio, Peyrin-Biroulet, Laurent, Panés, Julián, Phillips, Anne, Prescott, Natalie J., Proctor, Deborah D., Roberts, Rebecca, Russell, Richard, Rutgeerts, Paul, Sanderson, Jeremy, Sans, Miquel, Schumm, Philip, Seibold, Frank, Sharma, Yashoda, Simms, Lisa, Seielstad, Mark, Steinhart, A. Hillary, Targan, Stephan R., van den Berg, Leonard H., Vatn, Morten, Verspaget, Hein, Walters, Thomas, Wijmenga, Cisca, Wilson, David C., Westra, Harm-Jan, Xavier, Ramnik J., Zhao, Zhen Z., Ponsioen, Cyriel Y., Andersen, Vibeke, Torkvist, Leif, Gazouli, Maria, Anagnou, Nicholas P., Karlsen, Tom H., Kupcinskas, Limas, Sventoraityte, Jurgita, Mansfield, John C., Kugathasan, Subra, Silverberg, Mark S., Halfvarson, Jonas, Rotter, Jerome I., Mathew, Christopher G., Griffiths, Anne M., Gearry, Richard, Ahmad, Tariq, Brant, Steven R., Chamaillard, Mathias, Satsangi, Jack, Cho, Judy H., Schreiber, Stefan, Daly, Mark J., Barrett, Jeffrey C., Parkes, Miles, Annese, Vito, Hakonarson, Hakon, Radford-Smith, Graham, Duerr, Richard H., Vermeire, Séverine, Weersma, Rinse K., Rioux, John D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084597/
https://ncbi.nlm.nih.gov/pubmed/21297633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.764
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