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The Wnt/β-catenin Pathway Is Required for the Development of Leukemia Stem Cells in AML
A subset of cells called leukemia stem cells (LSCs) possess limitless self-renewal and are responsible for maintenance of leukemia. Selective eradication of LSCs could offer significant therapeutic benefit and there is great interest in identifying the signaling pathways that control their developme...
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| Main Authors: | , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3084586/ https://ncbi.nlm.nih.gov/pubmed/20339075 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1186624 |
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