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Two Structural and Functional Domains of MESD Required for Proper Folding and Trafficking of LRP5/6
How the ER folding machinery coordinates general and specialized chaperones during protein translation and folding remains an important unanswered question. Here, we show two structural domains in MESD, a specialized chaperone for LRP5/6, carry out dual functions. The chaperone domain forms a comple...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3084530/ https://ncbi.nlm.nih.gov/pubmed/21397183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2011.01.010 |
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