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Cooperative Folding and Ligand-binding Properties of LRP6 β-Propeller Domains
Wnt/β-catenin signaling controls cell growth during development, and its misregulation in adults can cause human diseases. LRP6, the essential co-receptor for the Wnt pathway, consists of four β-propeller domains flanked by epidermal growth factor repeats in its extracellular region. To understand t...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2685710/ https://ncbi.nlm.nih.gov/pubmed/19339249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807285200 |
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