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Emerging Bcl-2 inhibitors for the treatment of cancer
IMPORTANCE OF THE FIELD: Bcl-2 family proteins are a component of the anti-apoptotic machinery and are overexpressed in different malignancies. Accordingly, their enhanced expression has been attributed to the observed chemoresistance in most of the cancers. Therefore, targeting Bcl-2 family members...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3084453/ https://ncbi.nlm.nih.gov/pubmed/20812891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728214.2010.515210 |
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