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Non-Peptidic Small Molecule Inhibitors against Bcl-2 for Cancer Therapy

A critical regulator of the apoptotic machinery is the Bcl-2 family proteins whose over expression confers a protective effect on malignant cells against death signals of apoptosis. Cancer cells that are resistant to various anti-cancer drugs and treatment regimen are found to over express these Bcl...

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Autors principals: Azmi, Asfar S., Mohammad, Ramzi M.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577714/
https://ncbi.nlm.nih.gov/pubmed/18767026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.21567
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