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Does Positive Selection Drive Transcription Factor Binding Site Turnover? A Test with Drosophila Cis-Regulatory Modules

Transcription factor binding site(s) (TFBS) gain and loss (i.e., turnover) is a well-documented feature of cis-regulatory module (CRM) evolution, yet little attention has been paid to the evolutionary force(s) driving this turnover process. The predominant view, motivated by its widespread occurrenc...

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Main Authors: He, Bin Z., Holloway, Alisha K., Maerkl, Sebastian J., Kreitman, Martin
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084208/
https://ncbi.nlm.nih.gov/pubmed/21572512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002053
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