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Is Transcription Factor Binding Site Turnover a Sufficient Explanation for Cis-Regulatory Sequence Divergence?

The molecular evolution of cis-regulatory sequences is not well understood. Comparisons of closely related species show that cis-regulatory sequences contain a large number of sites constrained by purifying selection. In contrast, there are a number of examples from distantly related species where c...

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Bibliografiske detaljer
Main Authors: Venkataram, Sandeep, Fay, Justin C.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997565/
https://ncbi.nlm.nih.gov/pubmed/21068212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evq066
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