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A comparison of genomic copy number calls by Partek Genomics Suite, Genotyping Console and Birdsuite algorithms to quantitative PCR

BACKGROUND: Copy number variants are >1 kb genomic amplifications or deletions that can be identified using array platforms. However, arrays produce substantial background noise that contributes to high false discovery rates of variants. We hypothesized that quantitative PCR could finitely determ...

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Main Authors: Grayson, Britney L, Aune, Thomas M
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084167/
https://ncbi.nlm.nih.gov/pubmed/21489293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0381-4-8
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