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A multiply convergent platform for the synthesis of trioxacarcins

Many first-line cancer drugs are natural products or are derived from them by chemical modification. The trioxacarcins are an emerging class of molecules of microbial origin with potent antiproliferative effects, which may derive from their ability to covalently modify duplex DNA. All trioxacarcins...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Švenda, Jakub, Hill, Nicholas, Myers, Andrew G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084144/
https://ncbi.nlm.nih.gov/pubmed/21245350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1015257108
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