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Ammonia synthons for the multicomponent assembly of complex γ-lactams

The synthesis of γ-lactams that are unsubstituted at the 1-position (nitrogen) as well as their subsequent N-functionalization is reported. A recently discovered four-component reaction (4CR) is employed with either an ammonia precursor or a protected form of ammonia that can be deprotected in a sub...

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Autori principali: Tan, Darlene Q., Martin, Kevin S., Fettinger, James C., Shaw, Jared T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084106/
https://ncbi.nlm.nih.gov/pubmed/21289284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1015261108
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