TET2 Mutations Improve the New European LeukemiaNet Risk Classification of Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study

PURPOSE: To determine the frequency of TET2 mutations, their associations with clinical and molecular characteristics and outcome, and the associated gene- and microRNA-expression signatures in patients with primary cytogenetically normal acute myeloid leukemia (CN-AML). PATIENTS AND METHODS: Four-h...

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Hauptverfasser: Metzeler, Klaus H., Maharry, Kati, Radmacher, Michael D., Mrózek, Krzysztof, Margeson, Dean, Becker, Heiko, Curfman, John, Holland, Kelsi B., Schwind, Sebastian, Whitman, Susan P., Wu, Yue-Zhong, Blum, William, Powell, Bayard L., Carter, Thomas H., Wetzler, Meir, Moore, Joseph O., Kolitz, Jonathan E., Baer, Maria R., Carroll, Andrew J., Larson, Richard A., Caligiuri, Michael A., Marcucci, Guido, Bloomfield, Clara D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Clinical Oncology 2011
Schlagworte:
Original Reports
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084003/
https://ncbi.nlm.nih.gov/pubmed/21343549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2010.32.7742
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