FLT3 internal tandem duplication associates with adverse outcome and gene- and microRNA-expression signatures in patients 60 years of age or older with primary cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study

The clinical impact of FLT3-internal tandem duplications (ITDs), an adverse prognostic marker in adults aged < 60 years with primary cytogenetically normal acute myeloid leukemia (CN-AML), requires further investigation in older patients. In CN-AML patients aged ≥ 60 years treated on Cancer and L...

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Main Authors: Whitman, Susan P., Maharry, Kati, Radmacher, Michael D., Becker, Heiko, Mrózek, Krzysztof, Margeson, Dean, Holland, Kelsi B., Wu, Yue-Zhong, Schwind, Sebastian, Metzeler, Klaus H., Wen, Jing, Baer, Maria R., Powell, Bayard L., Carter, Thomas H., Kolitz, Jonathan E., Wetzler, Meir, Moore, Joseph O., Stone, Richard M., Carroll, Andrew J., Larson, Richard A., Caligiuri, Michael A., Marcucci, Guido, Bloomfield, Clara D.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2010
Teme:
Myeloid Neoplasia
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2981481/
https://ncbi.nlm.nih.gov/pubmed/20656931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-05-283648
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