Casein kinase 1 is required for efficient removal of Rec8 during meiosis I

Segregation of chromosomes during meiosis depends on separase cleavage of Rec8, the meiosis-specific alpha-kleisin subunit of cohesin. We mapped Rec8 phosphorylation sites by mass spectrometry and show that, in fission yeast, Rec8 phosphorylation is required for proper chromosome disjunction during...

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Hauptverfasser: Rumpf, Cornelia, Cipak, Lubos, Dudas, Andrej, Benko, Zsigmond, Pozgajova, Miroslava, Riedel, Christian G, Ammerer, Gustav, Mechtler, Karl, Gregan, Juraj
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2010
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083834/
https://ncbi.nlm.nih.gov/pubmed/20581463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.9.13.12146
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