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What makes centromeric cohesion resistant to separase cleavage during meiosis I but not during meiosis II?

Segregation of chromosomes during meiosis I is triggered by separase cleavage of the cohesin's Rec8 subunit along chromosome arms. Centromeric cohesin is protected from separase cleavage during meiosis I by Sgo1/MEI-S332 proteins in complex with protein phosphatase 2A (PP2A). This retention of...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Gregan, Juraj, Rumpf, Cornelia, Li, Zhang, Cipak, Lubos
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2007
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956405/
https://ncbi.nlm.nih.gov/pubmed/18256525
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