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What makes centromeric cohesion resistant to separase cleavage during meiosis I but not during meiosis II?
Segregation of chromosomes during meiosis I is triggered by separase cleavage of the cohesin's Rec8 subunit along chromosome arms. Centromeric cohesin is protected from separase cleavage during meiosis I by Sgo1/MEI-S332 proteins in complex with protein phosphatase 2A (PP2A). This retention of...
Shranjeno v:
| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2007
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2956405/ https://ncbi.nlm.nih.gov/pubmed/18256525 |
| Oznake: |
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