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Comparative study of mutagenesis by O6-methylguanine in the human Ha-ras oncogene in E. coli and in vitro.

Single residues of O6-methylguanine (O6-meG) were introduced into the first or second position of codon 12 (GGC; positions 12G1 or 12G2, respectively) or the first position of codon 13 (GGT; position 13G1) of the human Ha-ras oncogene in phage M13-based vectors. After transformation of E.coli, highe...

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Autori principali: Pletsa, V, Troungos, C, Souliotis, V L, Kyrtopoulos, S A
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1994
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC308379/
https://ncbi.nlm.nih.gov/pubmed/7937103
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