Sema3E-PlexinD1 signaling selectively suppresses disoriented angiogenesis in ischemic retinopathy in mice

During development, the retinal vasculature grows toward hypoxic areas in an organized fashion. By contrast, in ischemic retinopathies, new blood vessels grow out of the retinal surfaces without ameliorating retinal hypoxia. Restoration of proper angiogenic directionality would be of great benefit t...

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Autori principali: Fukushima, Yoko, Okada, Mitsuhiro, Kataoka, Hiroshi, Hirashima, Masanori, Yoshida, Yutaka, Mann, Fanny, Gomi, Fumi, Nishida, Kohji, Nishikawa, Shin-Ichi, Uemura, Akiyoshi
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083763/
https://ncbi.nlm.nih.gov/pubmed/21505259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI44900
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